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Symbol
Name
ID
Igf1r
insulin-like growth factor I receptor
MGI:96433
Phenotype annotations related to liver/biliary system
Darker colors indicate more annotations
Human Phenotypes
Hepatosplenomegaly
Micronodular cirrhosis
Subacute progressive viral hepatitis
Extrahepatic cholestasis
Jaundice
Neoplasm of the liver
Hepatocellular carcinoma
Disease(s) Associated with IGF1R
hepatocellular carcinoma
pancreatic cancer

Mouse Phenotypes
increased hepatocyte proliferation
increased liver weight
abnormal liver morphology
Availability Mouse Genotype
Igf1rhyft/Igf1rhyft
Igf1rtm1Jcbr/Igf1rtm1Jcbr
Tg(Fabp4-cre)1Abel/?  (conditional)
Igf1rtm1Jcbr/Igf1rtm1Jcbr
Ndor1Tg(UBC-cre/ERT2)1Ejb/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory